4-(Trifluoromethoxy)phenylmagnesium bromide
Magnesium, bromo[4-(trifluoromethoxy)phenyl]-
CAS: 169222-42-8
Molecular Formula: C7H4BrF3MgO
4-(Trifluoromethoxy)phenylmagnesium bromide - Names and Identifiers
4-(Trifluoromethoxy)phenylmagnesium bromide - Physico-chemical Properties
| Molecular Formula | C7H4BrF3MgO |
| Molar Mass | 265.3102696 |
| Density | 0.975 g/mL at 25 °C |
| Flash Point | -30°C |
4-(Trifluoromethoxy)phenylmagnesium bromide - Risk and Safety
| Risk Codes | R11 - Highly Flammable R14 - Reacts violently with water R19 - May form explosive peroxides R34 - Causes burns R40 - Limited evidence of a carcinogenic effect R37 - Irritating to the respiratory system |
| Safety Description | S16 - Keep away from sources of ignition. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | UN 2924 3/PG 2 |
| WGK Germany | 3 |
4-(Trifluoromethoxy)phenylmagnesium bromide - Introduction
Magnesium, bromo[4-(trifluoromethoxy)phenyl]-is an organic compound with the chemical formula C7H4BrF3OMg. The following is a description of the properties, uses, preparation and safety information of this compound:
Nature:
Magnesium, bromo[4-(trifluoromethoxy)phenyl]-is a white solid, soluble in organic solvents such as ether and dimethylformamide. It has low toxicity and strong magnesium-carbon bonds.
Use:
This compound is commonly used as a Grignard reagent in organic synthesis. Grignard reagents are usually obtained by reacting organic halides with magnesium and can be used to synthesize organic compounds such as carboxylic acids, aldehydes, ketones and olefins. Due to the special properties of Magnesium, bromo[4-(trifluoromethoxy)phenyl]-, it can be used to introduce trifluoromethoxy groups in the Grignard reaction, this Group has important application value in drug development and synthesis.
Method:
Magnesium, bromo[4-(trifluoromethoxy)phenyl]-can be obtained by reacting phenylmagnesium bromide with trifluoromethanol. First, phenylmagnesium bromide is reacted with trifluoromethanol in diethyl ether to give the product, Magnesium, bromo[4-(trifluoromethoxy)phenyl]-. Pay attention to safety during the reaction, avoid contact with skin and inhalation.
Safety Information:
Magnesium, bromo[4-(trifluoromethoxy)phenyl]-is a chemical reagent that should be stored properly to avoid contact with combustibles and oxidants. Wear appropriate personal protective equipment during handling and use, including protective glasses, protective gloves and laboratory coats. In case of contact with skin or eyes, rinse immediately with plenty of water. If inhaled or ingested by mistake, seek medical attention.
Summary:
Magnesium, bromo[4-(trifluoromethoxy)phenyl]-is an organic compound, commonly used as a Grignard reagent, with the special property of introducing trifluoromethoxy groups. Pay attention to safety measures during preparation and use, avoid contact with skin and eyes, and keep it properly.
Nature:
Magnesium, bromo[4-(trifluoromethoxy)phenyl]-is a white solid, soluble in organic solvents such as ether and dimethylformamide. It has low toxicity and strong magnesium-carbon bonds.
Use:
This compound is commonly used as a Grignard reagent in organic synthesis. Grignard reagents are usually obtained by reacting organic halides with magnesium and can be used to synthesize organic compounds such as carboxylic acids, aldehydes, ketones and olefins. Due to the special properties of Magnesium, bromo[4-(trifluoromethoxy)phenyl]-, it can be used to introduce trifluoromethoxy groups in the Grignard reaction, this Group has important application value in drug development and synthesis.
Method:
Magnesium, bromo[4-(trifluoromethoxy)phenyl]-can be obtained by reacting phenylmagnesium bromide with trifluoromethanol. First, phenylmagnesium bromide is reacted with trifluoromethanol in diethyl ether to give the product, Magnesium, bromo[4-(trifluoromethoxy)phenyl]-. Pay attention to safety during the reaction, avoid contact with skin and inhalation.
Safety Information:
Magnesium, bromo[4-(trifluoromethoxy)phenyl]-is a chemical reagent that should be stored properly to avoid contact with combustibles and oxidants. Wear appropriate personal protective equipment during handling and use, including protective glasses, protective gloves and laboratory coats. In case of contact with skin or eyes, rinse immediately with plenty of water. If inhaled or ingested by mistake, seek medical attention.
Summary:
Magnesium, bromo[4-(trifluoromethoxy)phenyl]-is an organic compound, commonly used as a Grignard reagent, with the special property of introducing trifluoromethoxy groups. Pay attention to safety measures during preparation and use, avoid contact with skin and eyes, and keep it properly.
Last Update：2024-04-09 21:32:38
